Molecular identification of Ca(2+)channels in human sperm

  title={Molecular identification of Ca(2+)channels in human sperm},
  author={Jin-Yong Park and H Ahn and Jung-Gyu Gu and Keun-Ho Lee and Jin-Sung Kim and Ho-Won Kang and Jung-ha Lee},
  journal={Experimental & Molecular Medicine},
The acrosome reaction is a Ca(2+)-dependent exocytotic process that is a prerequisite step for fertilization. External calcium entry through voltage-activated Ca(2+)channels is known to be essential in inducing the acrosome reaction of mammalian spermatozoa. Due to their complex geometry, however, electrophysiological identification of sperm Ca(2+)channels has been limited. Here we identified Ca(2+)channel mRNAs expressed in motile human sperm using RT-PCR and their levels were compared using… CONTINUE READING
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