Molecular identification and characterization of a and b forms of the glucocorticoid receptor.

@article{Yudt2001MolecularIA,
  title={Molecular identification and characterization of a and b forms of the glucocorticoid receptor.},
  author={Matthew R Yudt and John Anthony Cidlowski},
  journal={Molecular endocrinology},
  year={2001},
  volume={15 7},
  pages={1093-103}
}
The human glucocorticoid receptor (hGRalpha) is a ligand-activated transcription factor that mediates the physiological effects of corticosteroid hormones and is essential for life. Originally cloned in 1986, the transcriptionally active hGRalpha was reported to be a single protein species of 777 amino acids (molecular mass = 94 kDa). Biochemical data, obtained using various mammalian tissues and cell lines, however, have consistently revealed an additional, slightly smaller, second hGR protein… CONTINUE READING

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