Molecular heterosis: a review.

@article{Comings2000MolecularHA,
  title={Molecular heterosis: a review.},
  author={David E. Comings and James P. MacMurray},
  journal={Molecular genetics and metabolism},
  year={2000},
  volume={71 1-2},
  pages={
          19-31
        }
}
Molecular heterosis occurs when subjects heterozygous for a specific genetic polymorphism show a significantly greater effect (positive heterosis) or lesser effect (negative heterosis) for a quantitative or dichotomous trait than subjects homozygous for either allele. At a molecular level heterosis appears counterintuitive to the expectation that if the 1 allele of a two-allele polymorphism is associated with a decrease in gene expression, those carrying the 11 genotype should show the greatest… CONTINUE READING

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