Molecular genetics of pediatric soft tissue tumors: clinical application.

  title={Molecular genetics of pediatric soft tissue tumors: clinical application.},
  author={Chung-che Chang and Vinod B. Shidham},
  journal={The Journal of molecular diagnostics : JMD},
  volume={5 3},
The application of molecular genetics to pediatric soft tissue tumors has grown tremendously over the last decade. It has resulted in the identification of novel genes that have provided us with an increased understanding of oncogenesis. Furthermore, these findings have identified diagnostic and potentially prognostic factors for patient management. Molecular diagnostic techniques, such as reverse transcription PCR (RT-PCR) and fluorescence in situ hybridization (FISH), have become important… CONTINUE READING

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