Molecular genetics of human color vision: the genes encoding blue, green, and red pigments.

@article{Nathans1986MolecularGO,
  title={Molecular genetics of human color vision: the genes encoding blue, green, and red pigments.},
  author={Jeremy Nathans and D Thomas and David S. Hogness},
  journal={Science},
  year={1986},
  volume={232 4747},
  pages={
          193-202
        }
}
Human color vision is based on three light-sensitive pigments. The isolation and sequencing of genomic and complementary DNA clones that encode the apoproteins of these three pigments are described. The deduced amino acid sequences show 41 +/- 1 percent identity with rhodopsin. The red and green pigments show 96 percent mutual identity but only 43 percent identity with the blue pigment. Green pigment genes vary in number among color-normal individuals and, together with a single red pigment… 
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Recent gene conversion between genes encoding human red and green visual pigments.
TLDR
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The molecular basis of variation in human color vision
  • S. Deeb
  • Biology
    Clinical genetics
  • 2005
TLDR
Women who are heterozygous for red and green pigment genes that encode three spectrally distinct photopigments have the potential for enhanced color vision.
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Molecular genetics of inherited variation in human color vision.
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Interestingly, those portions of the polypeptide chain predicted to form loops on the cytoplasmic face of rhodopsin are perfectly conserved between the human and bovine proteins.
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