Molecular genetics of human color vision: the genes encoding blue, green, and red pigments.

@article{Nathans1986MolecularGO,
  title={Molecular genetics of human color vision: the genes encoding blue, green, and red pigments.},
  author={J. Nathans and D. Thomas and D. Hogness},
  journal={Science},
  year={1986},
  volume={232 4747},
  pages={
          193-202
        }
}
  • J. Nathans, D. Thomas, D. Hogness
  • Published 1986
  • Biology, Medicine
  • Science
  • Human color vision is based on three light-sensitive pigments. The isolation and sequencing of genomic and complementary DNA clones that encode the apoproteins of these three pigments are described. The deduced amino acid sequences show 41 +/- 1 percent identity with rhodopsin. The red and green pigments show 96 percent mutual identity but only 43 percent identity with the blue pigment. Green pigment genes vary in number among color-normal individuals and, together with a single red pigment… CONTINUE READING
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    References

    SHOWING 1-10 OF 38 REFERENCES
    Isolation and nucleotide sequence of the gene encoding human rhodopsin.
    • J. Nathans, D. Hogness
    • Biology, Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 1984
    • 434
    • PDF
    Topographic and active‐site studies on bovine rhodopsin
    • 24
    Flow of information in the light-triggered cyclic nucleotide cascade of vision.
    • B. Fung, J. Hurley, L. Stryer
    • Biology, Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 1981
    • 584
    • PDF