Molecular genetics of alcohol-related brain damage.

  title={Molecular genetics of alcohol-related brain damage.},
  author={Irene Guerrini and Allan D. Thomson and Hugh M. D. Gurling},
  journal={Alcohol and alcoholism},
  volume={44 2},
AIMS In the scientific literature it has been repeatedly hypothesized that there is a heritable susceptibility to thiamine deficiency comparable to other hereditary metabolic disorders. The aim of this paper is to review the most recent knowledge on the genetic susceptibility to the development of alcohol-related Wernicke-Korsakoff syndrome (WKS). METHODS A literature review was carried out looking at the molecular genetics studies performed in alcohol-dependent patients affected by WKS… CONTINUE READING


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Unraveling the pathophysiology of alcohol-induced thiamin deficiency.

American journal of physiology. Renal physiology • 2010
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Publications referenced by this paper.
Showing 1-10 of 48 references

Clinical signs

CG Harper, M Giles, R. Finlay-Jones
View 1 Excerpt
Highly Influenced

Abnormality of a thiamine-requiring enzyme in patients with Wernicke-Korsakoff syndrome.

The New England journal of medicine • 1977
View 8 Excerpts
Highly Influenced

The genetics of alcohol-related brain damage: from brain specimen to association studies

I Guerrini, A. Thomson
Alc Clin Exp Res • 2008

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