Molecular genetic aspects of solid tumors in childhood.

  title={Molecular genetic aspects of solid tumors in childhood.},
  author={Andrew M. Davidoff and Dana Ashley Hill},
  journal={Seminars in pediatric surgery},
  volume={10 3},
Advances in molecular genetic research in the past 2 decades have led to an increased understanding of the genetic events in the pathogenesis and progression of human malignancies, including those of childhood. A number of pediatric malignancies have served as models for the molecular genetic approach to patients with cancer. These have highlighted the utility of molecular analysis for a variety of purposes including diagnosis, risk stratification and treatment planning, understanding of… CONTINUE READING


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