Molecular genetic approaches to the targeted suppression of neuronal activity

  title={Molecular genetic approaches to the targeted suppression of neuronal activity},
  author={Benjamin White and Thomas P. Osterwalder and Haig Keshishian},
  journal={Current Biology},
Understanding how the diverse cells of the nervous system generate sensations, memories and behaviors is a profound challenge. This is because the activity of most neurons cannot easily be monitored or individually manipulated in vivo. As a result, it has been difficult to determine how different neurons contribute to nervous system function, even in simple organisms like Drosophila. Recent advances promise to change this situation by supplying molecular genetic tools for modulating neuronal… CONTINUE READING

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Nonet ML: A retrograde signal is involved in activitydependent remodeling at a C. elegans neuromuscular junction

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