Molecular genetic approaches to Alzheimer's disease.

  title={Molecular genetic approaches to Alzheimer's disease.},
  author={Rudolph E. Tanzi and Peter St George-Hyslop and James F. Gusella},
  journal={Trends in neurosciences},
  volume={12 4},
Alzheimer's disease (AD) has emerged in the past decade as a major public health problem. Epidemiological and neuropathological studies have revealed AD to be a very frequent disease associated with aging. Already the fourth leading cause of death in the USA and consuming a major component of health care costs, AD will take on even greater importance with the continuous growth of the elderly population. A concerted effort has been made in recent years to attack AD using an arsenal of powerful… CONTINUE READING