Molecular genetic analysis of apm-2 and aps-2, genes encoding the medium and small chains of the AP-2 clathrin-associated protein complex in the nematode Caenorhabditis elegans.

@article{Shim2000MolecularGA,
  title={Molecular genetic analysis of apm-2 and aps-2, genes encoding the medium and small chains of the AP-2 clathrin-associated protein complex in the nematode Caenorhabditis elegans.},
  author={Jae Woong Shim and Junho Lee},
  journal={Molecules and cells},
  year={2000},
  volume={10 3},
  pages={309-16}
}
In this report, we analyzed the apm-2 and aps-2 genes, which encode the nematode homologues of the medium chain and the small chain of the plasma membrane-associated clathrin-associated protein complex AP-2, respectively. We determined the genomic structure of the two genes. We show that apm-2 and aps-2 genes are expressed in most, if not all, cells during embryogenesis, and that the two genes are expressed primarily in neurons and some hypodermal cells following hatching through adulthood. RNA… CONTINUE READING

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