Molecular functions of human endogenous retroviruses in health and disease

  title={Molecular functions of human endogenous retroviruses in health and disease},
  author={Maria Suntsova and Andrew Garazha and Alena Ivanova and Dmitry Kaminsky and Alex Zhavoronkov and Anton Buzdin},
  journal={Cellular and Molecular Life Sciences},
Human endogenous retroviruses (HERVs) and related genetic elements form 504 distinct families and occupy ~8 % of human genome. Recent success of high-throughput experimental technologies facilitated understanding functional impact of HERVs for molecular machinery of human cells. HERVs encode active retroviral proteins, which may exert important physiological functions in the body, but also may be involved in the progression of cancer and numerous human autoimmune, neurological and infectious… CONTINUE READING
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