Molecular forms of prostate-specific antigen and human kallikrein 2 (hK2) in urine are not clinically useful for early detection and staging of prostate cancer.

@article{Pannek1997MolecularFO,
  title={Molecular forms of prostate-specific antigen and human kallikrein 2 (hK2) in urine are not clinically useful for early detection and staging of prostate cancer.},
  author={J{\"u}rgen Pannek and Harry G. Rittenhouse and Cindy L. Evans and Judith A. Finlay and Debra J Bruzek and Jafna Cox and Daniel Wai-Tin Chan and E N Subong and Alan W. Partin},
  journal={Urology},
  year={1997},
  volume={50 5},
  pages={715-21}
}
OBJECTIVES Prostate-specific antigen (PSA), a member of the human kallikrein (hK) family, is the most important tumor marker for early detection, staging, and monitoring of men with prostate cancer today. However, the sensitivity of serum PSA is not sufficient to be used alone for prostate cancer screening. Recently, it was reported that the serum-to-urinary total PSA ratio improves the detection of men with prostate cancer, especially in men with a serum total PSA level between 4.0 and 10.0 ng… CONTINUE READING
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