Molecular feminization of mouse seminal vesicle by prenatal exposure to diethylstilbestrol: altered expression of messenger RNA.

@article{Beckman1994MolecularFO,
  title={Molecular feminization of mouse seminal vesicle by prenatal exposure to diethylstilbestrol: altered expression of messenger RNA.},
  author={William C. Beckman and Retha R. Newbold and Christina T. Teng and J A McLachlan},
  journal={The Journal of urology},
  year={1994},
  volume={151 5},
  pages={
          1370-8
        }
}
Exposure to estrogens during critical stages of development has been reported to cause irreversible changes in estrogen target tissues such as the reproductive tract. In fact, recent studies using mice describe prenatal estrogen exposure resulting in the expression of the major estrogen-inducible uterine secretory protein, lactoferrin (LF), by the seminal vesicles of the male offspring. Thus, we have studied the role of estrogens in abnormal and normal gene expression in the developing male… CONTINUE READING

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