Molecular features of colorectal hyperplastic polyps and sessile serrated adenoma/polyps from Korea.

@article{Kim2011MolecularFO,
  title={Molecular features of colorectal hyperplastic polyps and sessile serrated adenoma/polyps from Korea.},
  author={Hee C Kim and Eui Jin Lee and Sangyun Ha and So Young Kang and Kee-Taek Jang and Cheol Keun Park and Jin Yong Kim and Young Ho Kim and Dong Kyung Chang and Robert D Odze},
  journal={The American journal of surgical pathology},
  year={2011},
  volume={35 9},
  pages={1274-86}
}
Abundant recent data suggest that sessile serrated adenoma/polyp (SSA/P) is an early precursor lesion in the serrated pathway of carcinogenesis. It is believed that SSA/Ps develop cancer by an SSA/P-dysplasia-carcinoma sequence. Hyperplastic polyps (HPs) share some histologic and molecular characteristics with SSA/P, but it is unclear whether SSA/Ps are derived from HPs or whether they develop by a different pathogenetic pathway. Previous studies have shown that serrated polyps from Korean… CONTINUE READING

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