Molecular evolution of the HBII-52 snoRNA cluster.

Abstract

HBII-52 is a human brain-specific C/D box snoRNA that potentially regulates the editing and/or alternative splicing of the serotonin receptor. Forty-two nearly identical copies of the HBII-52 gene are located immediately downstream of the SNRPN protein-coding gene in an imprinted locus associated with Prader-Willi syndrome. Other eutherian mammals, with… (More)
DOI: 10.1016/j.jmb.2008.06.057

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