Molecular evolution of the ATP-binding cassette subfamily G member 2 gene subfamily and its paralogs in birds

@article{Ma2020MolecularEO,
  title={Molecular evolution of the ATP-binding cassette subfamily G member 2 gene subfamily and its paralogs in birds},
  author={Shengchao Ma and He-he Liu and Wenqiang Sun and Ahsan Mustafa and Yang Xi and Fajun Pu and Yanying Li and Chunchun Han and Lili Bai and He Hua},
  journal={BMC Evolutionary Biology},
  year={2020},
  volume={20}
}
Background ATP-binding cassette (ABC) transporters are involved in the active transportation of various endogenous or exogenous substances. Two ABCG2 gene subfamily members have been identified in birds. A detailed comparative study of the ABCG2 and ABCG2-like genes aid our understanding of their evolutionary history at the molecular level and provide a theoretical reference for studying the specific functions of ABCG2 and ABCG2-like genes in birds. Results We first identified 77 ABCG2 / ABCG2… 
2 Citations

Genomic variation in the Black-throated Green Warbler (Setophaga virens) suggests divergence in a disjunct Atlantic Coastal Plain population (S. v. waynei)

The results, combined with previously documented ecological and morphological distinctiveness, support that S. v. waynei be considered a distinct and recognized subspecies worthy of targeted conservation efforts.

Defence mitigation by predators of chemically defended prey integrated over the predation sequence and across biological levels with a focus on cardiotonic steroids

It is shown that distinct lineages of predators have evolved dissecting behaviour, changes in perception of risk and of taste perception, and target-site insensitivity, and the predation sequence framework will be useful for organizing future studies of chemically mediated systems and coevolution.

References

SHOWING 1-10 OF 67 REFERENCES

Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates.

Characterization of all ABC transporters from the human genome and from model organisms will lead to additional insights into normal physiology and human disease.

Evolution of the vertebrate ABC gene family: analysis of gene birth and death.

Combined phylogeny and neighborhood analysis of the evolution of the ABC transporters conferring multiple drug resistance in hemiascomycete yeasts

The neighborhood analysis provides an efficient method to trace the history of genes and disentangle the orthology and paralogy relationships in the pleiotropic drug resistance proteins (Pdrp) subfamily.

Tracing the structural evolution of eukaryotic ATP binding cassette transporter superfamily

A putative structural evolutionary path of eukaryote ABC transporters is presented that will increase the understanding on their origin, divergence and function.

Oligomerization of the human ABC transporter ABCG2: evaluation of the native protein and chimeric dimers.

It is shown that although extracellular disulfide bonds may exist between monomers, they are not essential for ABCG2 localization, transport activity, or prazosin-stimulated ATPase activity, and suggest that ABCG 2 functions as a dimer, but do not exclude functional higher order oligomers.

Whole-Genome Identification, Phylogeny, and Evolution of the Cytochrome P450 Family 2 (CYP2) Subfamilies in Birds

There has been active enzyme site selection on CYP2 subfamilies and differential selection associated with different life history traits among birds, and selective constraint variations in some avian CYP1 subfam families are consistentlyassociated with different feeding habits, habitats, and migratory behaviors.

Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system.

It is suggested that multidrug transporters are essential parts of an innate defense system, the "chemoimmunity" network, which has a number of features reminiscent of classical immunology.

ABC transporter research: going strong 40 years on

This Biochemical Society Focused Meeting brought together researchers with diverse experimental approaches and with different fundamental questions, all of which are linked by the commonality of ABC transporters.

Genome-wide organization and expression profiling of the R2R3-MYB transcription factor family in pineapple (Ananas comosus)

The comprehensive expression analysis of the pineapple MYB genes, especially the tissue-preferential and stress-responsive genes, could provide valuable clues for further function characterization and contribute to the greater understanding of their biological roles in pineapple.

The product of the ABC half-transporter gene ABCG2 (BCRP/MXR/ABCP) is expressed in the plasma membrane.

This protein is highly overexpressed in several drug-resistant cell lines and localizes predominantly to the plasma membrane, instead of to intracellular membranes as seen with all other known half-transporters.
...