Molecular evolution of lytic enzymes of Streptococcus pneumoniae and its bacteriophages.

@article{Garca1988MolecularEO,
  title={Molecular evolution of lytic enzymes of Streptococcus pneumoniae and its bacteriophages.},
  author={Enrique Garc{\'i}a and Jos{\'e} L Garc{\'i}a and Pedro Garc{\'i}a and A Arrar{\'a}s and Jos{\'e} Mar{\'i}a S{\'a}nchez-Puelles and R. Vara Lopez},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1988},
  volume={85 3},
  pages={914-8}
}
A 2.9-kilobase Acc I fragment of the DNA of the pneumococcal bacteriophage Cp-1, containing the cpl gene, hybridizes with the lytA gene encoding the pneumococcal amidase. The nucleotide sequence of the cpl gene of Cp-1, encoding a muramidase (CPL), has been determined. The 3' regions of the cpl and lytA coding sequences show considerable nucleotide sequence homology and the carboxyl-terminal domains of the deduced amino acid sequences of these lysins are quite similar: 73 of the carboxyl… CONTINUE READING