Molecular evolution of group II phospholipases A2

  title={Molecular evolution of group II phospholipases A2},
  author={Tomohisa Ogawa and Masato Kitajima and Kin-ichi Nakashima and Yoshiyuki Sakaki and Motonori Ohno},
  journal={Journal of Molecular Evolution},
The nucleotide sequences of 13 cDNAs encoding group II phospholipases A2 (PLA2 S), which are from viperidae snake venoms and from mammalian sources, were aligned and analyzed by phylogenetic trees constructed using various components of the sequences. The evolutionary trees derived from the combined sequences of the untranslated (5′ and 3′) region and the signal peptide region of cDNAs were in accord with the consequences from taxonomy. In contrast, the evolutionary trees from the mature… CONTINUE READING


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