Molecular events in the activation of murine macrophages

  title={Molecular events in the activation of murine macrophages},
  author={R. J. Uhing and Dolph O. Adams},
  journal={Agents and Actions},
Recent studies have identified some of the early molecular transductional events, which occur during the activation of murine macrophages. Our current evidence indicate a central role for protein kinase C for the priming effect of interferon-γ (IFNγ). IFNγ also initiates Na+/H+ exchange and45Ca efflux from murine macrophages (cascade 1). Our data further… CONTINUE READING