Molecular events in kidney ageing.

  title={Molecular events in kidney ageing.},
  author={Konrad S. Famulski and Phillip F Halloran},
  journal={Current opinion in nephrology and hypertension},
  volume={14 3},
PURPOSE OF REVIEW Ageing of the kidney is a problem of clinical and basic interest. The problem of renal dysfunction and end-stage renal disease is a major burden on the health system, and old donor age is a major limitation on the use of donor organs and on survival of transplanted kidneys. Moreover, stresses linked to nephropathies, postoperative stress, inflammation and allograft rejection can lead to premature senescence of renal cells thus accelerating organ atrophy. Age-related and… CONTINUE READING
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