Molecular events in follicular thyroid tumors.

  title={Molecular events in follicular thyroid tumors.},
  author={Todd G. Kroll},
  journal={Cancer treatment and research},
Knowledge of the molecular events that govern human thyroid tumorigenesis has grown considerably in the past ten years. Key genetic alterations and new oncogenic pathways have been identified. Molecular genetic aberrations in thyroid carcinomas bear noteworthy resemblance to those in acute myelogenous leukemias. Thyroid carcinomas and myeloid leukemias both possess transcription factor gene rearrangements-PPARgamma-related translocations in thyroid carcinoma and RARalpha-related and CBF-related… CONTINUE READING


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