Molecular events in B lymphocyte activation: consequences of signals transduced through MHC class II molecules.

@article{Baluyut1993MolecularEI,
  title={Molecular events in B lymphocyte activation: consequences of signals transduced through MHC class II molecules.},
  author={A R Baluyut and Karen E. Pollok and Subbarao Bondada},
  journal={Cellular immunology},
  year={1993},
  volume={147 2},
  pages={353-66}
}
Evidence is presented to demonstrate that murine B lymphocytes receive growth stimulatory signals from their surface class II molecules. Monoclonal anti-Ia antibodies enhanced anti-mu-induced B cell proliferative response. The signals through surface immunoglobulin (Ig) and Ia appeared to act sequentially since preexposure to anti-mu was required to observe… CONTINUE READING