Molecular epidemiology reveals genetic diversity among 363 isolates of the Cryptococcus neoformans and Cryptococcus gattii species complex in 61 Ivorian HIV-positive patients.

@article{Kassi2016MolecularER,
  title={Molecular epidemiology reveals genetic diversity among 363 isolates of the Cryptococcus neoformans and Cryptococcus gattii species complex in 61 Ivorian HIV-positive patients.},
  author={Fulgence Kondo Kassi and Pascal Drakulovski and Virginie Bellet and Donika Krasteva and François Gatchitch and Adama Doumbia and Gis{\`e}le A. Kouakou and Eric Delaporte and J. Reynes and Mich{\`e}le Malli{\'e} and Herv{\'e} I. E. Menan and S{\'e}bastien Bertout},
  journal={Mycoses},
  year={2016},
  volume={59 12},
  pages={811-817}
}
Cryptococcal meningitis is a severe opportunistic infection in HIV-infected patients. In Ivory Coast, despite the availability of antiretroviral treatment (ART), this infection is still prevalent. The study investigates the genetic diversity of 363 clinical isolates of Cryptococcus from 61 Ivorian HIV-positive patients, the occurrence of mixed infections and the in vitro antifungal susceptibility of the isolates. Serotyping was performed via LAC1 and CAP64 gene amplification. Genotyping was… CONTINUE READING
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