Molecular epidemiology of tuberculosis in a rural area of high prevalence in South India: implications for disease control and prevention.

@article{Narayanan2002MolecularEO,
  title={Molecular epidemiology of tuberculosis in a rural area of high prevalence in South India: implications for disease control and prevention.},
  author={Sujatha Narayanan and Sulochana D. Das and Renu Garg and Lalitha Hari and V Bala Bhaskara Rao and Thomas R Frieden and P. R. Narayanan},
  journal={Journal of clinical microbiology},
  year={2002},
  volume={40 12},
  pages={4785-8}
}
Molecular and conventional epidemiologic techniques were used to study the mechanisms and risk factors for tuberculosis transmission in a rural area with high prevalence in south India. Restriction fragment length polymorphism analysis with IS6110 and direct repeat probes was performed with 378 Mycobacterium tuberculosis isolates from patients. Forty-one percent of M. tuberculosis isolates harbored a single copy of IS6110. Of 378 patients, 236 had distinct strains; 142 (38%) shared a strain… CONTINUE READING

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