Molecular epidemiology of human cancer: contribution of mutation spectra studies of tumor suppressor genes.

The identification of individuals at high risk of cancer can offer promising avenues for the prevention of cancer. The majority of human cancer cases are caused by environmental, occupational, and recreational exposures to carcinogens (1). These carcinogens can affect one or multiple stages of carcinogenesis through both genetic and epigenetic mechanisms (2… CONTINUE READING