Molecular epidemiology of drug-resistant malaria in western Kenya highlands

@article{Zhong2008MolecularEO,
  title={Molecular epidemiology of drug-resistant malaria in western Kenya highlands},
  author={Daibin Zhong and Yaw Asare Afrane and Andrew K. Githeko and Liwang Cui and David M. Menge and Guiyun Yan},
  journal={BMC Infectious Diseases},
  year={2008},
  volume={8},
  pages={105 - 105}
}
BACKGROUND Since the late 1980s a series of malaria epidemics has occurred in western Kenya highlands. Among the possible factors that may contribute to the highland malaria epidemics, parasite resistance to antimalarials has not been well investigated. METHODS Using parasites from highland and lowland areas of western Kenya, we examined key mutations associated with Plasmodium falciparum resistance to sulfadoxine - pyrimethamine and chloroquine, including dihydrofolate reductase (pfdhfr) and… CONTINUE READING