Molecular epidemiology of dengue type 3 virus in Brazil and Paraguay, 2002-2004.

@article{Aquino2006MolecularEO,
  title={Molecular epidemiology of dengue type 3 virus in Brazil and Paraguay, 2002-2004.},
  author={Victor Hugo Aquino and Elen Anatriello and Paula Fernanda Gonçalves and Eliana Vieira Pinto da Silva and Pedro F. C. Vasconcelos and Deusylene S Vieira and Weber Cheli Batista and Maria Liz Bobadilla and Cynthia V{\'a}zquez and Mirian Moran and Luiz Tadeu Moraes Figueiredo},
  journal={The American journal of tropical medicine and hygiene},
  year={2006},
  volume={75 4},
  pages={710-5}
}
We studied the molecular epidemiology of dengue virus type 3 (DENV-3) in Brazil and Paraguay by analyzing the 5' and 3' untranslated regions (5' and 3'UTRs) and the E protein gene of viruses isolated between 2002 and 2004. Both 5' and 3'UTRs were highly conserved. However, the 3'UTR of two isolates from Brazil contained eight nucleotide deletions compared with the remaining 26 viruses. Phylogenetic analyses suggested that DENV-3 was introduced into Brazil from the Caribbean Islands at least… CONTINUE READING

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