Molecular epidemiology of aflatoxin exposures: validation of aflatoxin-N7-guanine levels in urine as a biomarker in experimental rat models and humans.

@article{Groopman1993MolecularEO,
  title={Molecular epidemiology of aflatoxin exposures: validation of aflatoxin-N7-guanine levels in urine as a biomarker in experimental rat models and humans.},
  author={John D. Groopman and Christopher Paul Wild and J J Hasler and C Junshi and Gerald N. Wogan and Thomas Wells Kensler},
  journal={Environmental Health Perspectives},
  year={1993},
  volume={99},
  pages={107 - 113}
}
Human epidemiology and experimental animal data have provided the statistical association and biological information necessary to propose that aflatoxins are risk factors for human liver cancer. As liver cancer causes at least 200,000 deaths per year, prevention measures must be developed to ameliorate this nearly always fatal disease. Preventive strategies will be facilitated by the identification of individuals at high risk. It is the goal of the molecular dosimetry field to provide facile… CONTINUE READING

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Effect of 1 , 2 - dithiole - 3 - thione , a monofunctional enzyme inducer , on aflatoxin - DNA adduct formation in rat liver

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