Molecular epidemiology of Coxsackievirus A16 strains isolated from children in Yamagata, Japan between 1988 and 2011.

@article{Mizuta2013MolecularEO,
  title={Molecular epidemiology of Coxsackievirus A16 strains isolated from children in Yamagata, Japan between 1988 and 2011.},
  author={Katsumi Mizuta and Chieko Abiko and Yoko Aoki and Tatsuya Ikeda and Yoko Matsuzaki and Seiji Hongo and Tsutomu Itagaki and Noriko Katsushima and Akira Ohmi and Hidekazu Nishimura and Tadayuki Ahiko},
  journal={Microbiology and immunology},
  year={2013},
  volume={57 5},
  pages={400-5}
}
To clarify the longitudinal molecular epidemiology of coxsackievirus A16, phylogenetic analysis based on the VP1 region of 220 isolates in Yamagata, Japan was performed. The resultant phylogenetic tree indicates that the Yamagata isolates and reference strains can be readily genotyped into three genogroups, and 0, 12 and 208 isolates belonged to the first, second, and third genogroups, respectively. The first genogroup includes only the prototype strain, the second strains that had disappeared… CONTINUE READING

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Genetic changes of coxsackievirus A 16 and enterovirus 71 isolated from hand , foot and mouth disease patients in Toyama , Japan between 1981 and 2007

S. Zhu
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