Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Chinese hospitals.

@article{Wang2010MolecularEA,
  title={Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Chinese hospitals.},
  author={Jie Wang and Jianying Zhou and Ting-ting Qu and Ping Shen and Ze-qing Wei and Yunsong Yu and Lanjuan Li},
  journal={International journal of antimicrobial agents},
  year={2010},
  volume={35 5},
  pages={486-91}
}
We investigated the molecular epidemiology and carbapenem resistance mechanisms of 258 non-duplicate carbapenem-resistant clinical isolates of Pseudomonas aeruginosa collected from 2006 to 2007 at 28 hospitals in China. Up to 88% of the carbapenem-resistant isolates were multidrug-resistant. Pulsed-field gel electrophoresis (PFGE) revealed that levels of intrahospital and interhospital dissemination of clones were low. To assess the mechanisms leading to resistance, all 258 carbapenem-resistant… CONTINUE READING

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