Molecular epidemiology and mechanisms of carbapenem resistance in Acinetobacter baumannii endemic in New York City.

@article{Quale2003MolecularEA,
  title={Molecular epidemiology and mechanisms of carbapenem resistance in Acinetobacter baumannii endemic in New York City.},
  author={John M Quale and Simona Bratu and David Landman and Renuka Heddurshetti},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2003},
  volume={37 2},
  pages={214-20}
}
Multidrug-resistant Acinetobacter baumannii has emerged as a serious nosocomial pathogen in certain areas. In Brooklyn, New York, citywide surveillance revealed that approximately 2 of every 3 isolates were resistant to carbapenem antibiotics. Genetic fingerprinting revealed that 2 strains accounted for 82% of these resistant isolates. Compared with carbapenem-susceptible isolates, carbapenem-resistant isolates had reduced expression of 47-, 44-, and 37-kDa outer-membrane proteins. No specific… CONTINUE READING

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