Molecular epidemiological studies of human herpesvirus 6 in families.

  title={Molecular epidemiological studies of human herpesvirus 6 in families.},
  author={Tetsu Mukai and Tomohiro Yamamoto and Toshio Kondo and Kazuhiro Kondo and Toshiomi Okuno and Haruhiko Kosuge and Koichi Yamanishi},
  journal={Journal of medical virology},
  volume={42 3},
The mode of transmission of human herpesvirus 6 (HHV-6) was investigated by molecular epidemiological techniques in four families. HHV-6 was isolated from the peripheral blood of seven infants with exanthem subitum, including siblings, and from the saliva of two mothers. These isolates were examined for genetic relatedness by means of restriction enzymes analysis of purified DNA. While the profiles of the digestion patterns differed among families, they were very similar in a particular family… CONTINUE READING

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