Molecular epidemiologic characteristics of Streptococcus pneumoniae isolates from children with meningitis in Japan from 2007 through 2009.

@article{Sakai2011MolecularEC,
  title={Molecular epidemiologic characteristics of Streptococcus pneumoniae isolates from children with meningitis in Japan from 2007 through 2009.},
  author={Fuminori Sakai and Naoko Chiba and Akiko Ono and Somay Yamagata Murayama and Kimiko Ubukata and Keisuke Sunakawa and Takashi Takahashi},
  journal={Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy},
  year={2011},
  volume={17 3},
  pages={334-40}
}
We examined associations of serotypes with multilocus sequence typing (MLST) data for 7 housekeeping genes and the genotype concerning penicillin resistance based on penicillin-binding protein (PBP) alterations in Streptococcus pneumoniae isolates from children with meningitis. From throughout Japan, we collected 115 pneumococcal isolates from the cerebrospinal fluid of patients 15 years old or younger from January 2007 to December 2009. We then carried out serotyping, MLST, and genotypic… CONTINUE READING