Molecular engineering of streptavidin.

  title={Molecular engineering of streptavidin.},
  author={Takeshi Sano and Sandor Vajda and Gabriel O. Reznik and Carolyn L. Smith and Charles R. Cantor},
  journal={Annals of the New York Academy of Sciences},
Streptavidin is a tetrameric protein produced by the bacterium Streptomyces avidinii; it has great similarity to the chicken protein avidin.14 These proteins bind the vitamin biotin with an extremely high affinity. The dissociation constant of streptavidin-biotin and avidin-biotin complexes is estimated at around M;3.4 this is one of the tightest… CONTINUE READING