Molecular engineering of an orthopaedic implant: from bench to bedside.

Abstract

The use of metallic implants has revolutionised the practice of orthopaedic surgery. While the safety and biocompatibility of these devices are excellent, a small percentage becomes infected. These infections are due to the formation of a biofilm that harbours bacteria encased in a complex extracellular matrix. The matrix serves as a barrier to immune… (More)

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Cite this paper

@article{Shapiro2012MolecularEO, title={Molecular engineering of an orthopaedic implant: from bench to bedside.}, author={Irving M. Shapiro and Noreen J. Hickok and Javad Parvizi and Sara Stewart and Thomas P. Schaer}, journal={European cells & materials}, year={2012}, volume={23}, pages={362-70} }