Molecular ecological analysis of dietary and antibiotic-induced alterations of the mouse intestinal microbiota.

@article{McCracken2001MolecularEA,
  title={Molecular ecological analysis of dietary and antibiotic-induced alterations of the mouse intestinal microbiota.},
  author={Vance J. McCracken and Joyce M Simpson and R. I. Mackie and H. Rex Gaskins},
  journal={The Journal of nutrition},
  year={2001},
  volume={131 6},
  pages={1862-70}
}
A cultivation-independent approach, polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE), was used to characterize changes in fecal bacterial populations resulting from consumption of a low residue diet or oral administration of a broad-spectrum antibiotic. C57BL/6NHsd mice were weaned to either a standard nonpurified diet (LC-diet) or a low residue diet (LR-diet) and at 17 wk of age were randomly assigned to receive drinking water with or without 25 ppm cefoxitin for 14… CONTINUE READING

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