Molecular-dynamics simulations for amyloid beta 1-42 monomer with D-aspartic acid residues using continuous solvent.


Molecular-dynamics simulations of amyloid-beta(1-42) peptides including D-aspartic acid residues were performed, and their three-dimensional structures were compared. The simulations were performed in an aqueous environment using a continuous solvent model. In the structures obtained from simulations, the occurrence ratio of beta-extended structures for the… (More)
DOI: 10.1002/cbdv.200900299