Molecular diversity of cell-matrix adhesions.

  title={Molecular diversity of cell-matrix adhesions.},
  author={Eli Zamir and Ben Zion Katz and Shin-ichi Aota and Kenneth M Yamada and Benjamin Geiger and Zvi Kam},
  journal={Journal of cell science},
  volume={112 ( Pt 11)},
In this study we have examined for molecular heterogeneity of cell-matrix adhesions and the involvement of actomyosin contractility in the selective recruitment of different plaque proteins. For this purpose, we have developed a novel microscopic approach for molecular morphometry, based on automatic identification of matrix adhesions, followed by quantitative immunofluorescence and morphometric analysis. Particularly informative was fluorescence ratio imaging, comparing the local labeling… CONTINUE READING
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