Molecular dissection of cis-regulatory modules at the Drosophila bithorax complex reveals critical transcription factor signature motifs.

Abstract

At the Drosophila melanogaster bithorax complex (BX-C) over 330kb of intergenic DNA is responsible for directing the transcription of just three homeotic (Hox) genes during embryonic development. A number of distinct enhancer cis-regulatory modules (CRMs) are responsible for controlling the specific expression patterns of the Hox genes in the BX-C. While it… (More)
DOI: 10.1016/j.ydbio.2011.07.028

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Cite this paper

@article{Starr2011MolecularDO, title={Molecular dissection of cis-regulatory modules at the Drosophila bithorax complex reveals critical transcription factor signature motifs.}, author={Michael O. Starr and Margaret C W Ho and Eric Gunther and Yen-Kuei Tu and Andrey S. Shur and Sara E. Goetz and Matthew J Borok and Victoria Kang and Robert A. Drewell}, journal={Developmental biology}, year={2011}, volume={359 2}, pages={290-302} }