Molecular differentiation of schizoaffective disorder from schizophrenia using BDNF haplotypes.

@article{Lencz2009MolecularDO,
  title={Molecular differentiation of schizoaffective disorder from schizophrenia using BDNF haplotypes.},
  author={Todd Lencz and Robert H. Lipsky and Pamela Derosse and Katherine E. Burdick and John M. Kane and Anil K. Malhotra},
  journal={The British journal of psychiatry : the journal of mental science},
  year={2009},
  volume={194 4},
  pages={
          313-8
        }
}
BACKGROUND Allelic variation in the gene encoding brain-derived neurotrophic factor (BDNF) has been associated with affective disorders, but generally not schizophrenia. Brain-derived neurotrophic factor variants may help clarify the status of schizoaffective disorder. AIMS To test the hypothesis that BDNF haplotypes are associated with psychiatric illness marked by a prominent affective component. METHOD Frequencies of a 5-marker BDNF haplotype were examined in 600 White participants… CONTINUE READING

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