Molecular differences in the microsatellite stable phenotype between left‐sided and right‐sided colorectal cancer

@inproceedings{Takahashi2016MolecularDI,
  title={Molecular differences in the microsatellite stable phenotype between left‐sided and right‐sided colorectal cancer},
  author={Yayoi Takahashi and Tamotsu Sugai and Wataru Habano and Kazuyuki Ishida and Makoto Eizuka and Koki Otsuka and Akira Sasaki and Takayuki Matsumoto and Takanori Morikawa and Michiaki Unno and Hiromu Suzuki},
  booktitle={International journal of cancer},
  year={2016}
}
Differences in the pathogenesis of microsatellite stable (MSS) sporadic colorectal cancers (CRCs) between left-sided CRC (LC) and right-sided CRC (RC) have not been clarified. To identify pathogenesis-related genomic differences between MSS CRCs within the two locations, we performed a comprehensive molecular analysis using crypt isolation with samples from 92 sporadic CRCs. Microsatellite instability (MSI; high and low/negative) and DNA methylation status (low methylation epigenome… CONTINUE READING
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