Molecular diagnostics in acute leukemias

  title={Molecular diagnostics in acute leukemias},
  author={U. Bacher and S. Schnittger and C. Haferlach and T. Haferlach},
  booktitle={Clinical chemistry and laboratory medicine},
  • U. Bacher, S. Schnittger, +1 author T. Haferlach
  • Published in
    Clinical chemistry and…
  • Medicine
  • Abstract Acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) both represent highly heterogeneous entities on the basis of diverse cyto- and molecular genetic alterations with considerable influence on prognosis and therapeutic decisions. In recent years, insights into the complex network of molecular markers underlying this diversity have shown marked progress due to the detection of novel mutations, such as nucleophosmin gene (NPM1) in AML, and due to the description of… CONTINUE READING
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