Molecular diagnosis of sentinel lymph node metastases in cervical cancer using squamous cell carcinoma antigen.

@article{Yuan2008MolecularDO,
  title={Molecular diagnosis of sentinel lymph node metastases in cervical cancer using squamous cell carcinoma antigen.},
  author={Song-Hua Yuan and Xue-Fang Liang and Wei-Hua Jia and Jian-ling Huang and Mei Wei and Ling Deng and Li-zhi Liang and Xiao-Yun Wang and Yi-xin Zeng},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2008},
  volume={14 17},
  pages={5571-8}
}
PURPOSE To clarify the prognostic value of molecular diagnosis of SLN metastases in cervical cancer using SCCA. EXPERIMENTAL DESIGN All SLNs and primary tumors, part of non-SLNs, were harvested from 36 patients with cervical cancer. Expression levels of SCCA, cytokeratin 19 (CK19), and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA in 178 samples (29 primary tumors, 5 histologic positive nodes, 60 histologic negative SLNs, 69 non-SLNs, and 15 normal nodes) were assessed by quantitative… CONTINUE READING

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