Molecular diagnosis of lymphoid malignancies by gene expression profiling.

@article{Davis2002MolecularDO,
  title={Molecular diagnosis of lymphoid malignancies by gene expression profiling.},
  author={R Eric Davis and Louis M. Staudt},
  journal={Current opinion in hematology},
  year={2002},
  volume={9 4},
  pages={333-8}
}
Gene expression profiling using DNA microarrays has great potential to improve the understanding, diagnosis, and management of lymphomas, leukemias, and other malignancies. Gene expression profiling studies of diffuse large B-cell lymphoma (DLBCL) have shown that this diagnostic category encompasses at least two molecularly distinct diseases, differing in differentiation stage (cell of origin), oncogenic mechanisms, and clinical outcome. Gene expression profiling revealed that the antiapoptotic… CONTINUE READING
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