Molecular diagnosis of human prion disease.

  title={Molecular diagnosis of human prion disease.},
  author={Isabelle Quadrio and Armand Perret-Liaudet and Gabor G Kovacs},
  journal={Expert opinion on medical diagnostics},
  volume={5 4},
INTRODUCTION Human prion diseases (PrDs) are transmissible fatal nervous system disorders with public health implications. They are characterized by the presence of a disease-associated form of the physiological cellular prion protein. Development of diagnostic procedures is important to avoid transmission, including through blood products. Methods used for the detection of disease-associated PrP have implications for other neurodegenerative diseases. AREAS COVERED In this review, the authors… CONTINUE READING