Molecular diagnosis of early pancreatic ductal adenocarcinoma in high-risk patients.

@article{Wong2001MolecularDO,
  title={Molecular diagnosis of early pancreatic ductal adenocarcinoma in high-risk patients.},
  author={Theresa M Wong and Nathan R Howes and Jane Threadgold and Howard L Smart and Martin G Lombard and Ian Gilmore and Robert Sutton and William Greenhalf and Ian Ellis and John P Neoptolemos},
  journal={Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]},
  year={2001},
  volume={1 5},
  pages={486-509}
}
The prevalence of pancreatic cancer in the general population is too low--even in high-prevalence areas such as Northern Europe and North America (8-12 per 10(5) population)--relative to the diagnostic accuracy of present detection methods to permit primary screening in the asymptomatic adult population. The recognition that the lifetime risk of developing pancreatic cancer for patients with hereditary pancreatitis (HP) is extremely high (20% by the age of 60 years and 40% by the age of 70… CONTINUE READING