Molecular diagnosis of Legionella infections--Clinical utility of front-line screening as part of a pneumonia diagnostic algorithm.

@article{Gadsby2016MolecularDO,
  title={Molecular diagnosis of Legionella infections--Clinical utility of front-line screening as part of a pneumonia diagnostic algorithm.},
  author={Naomi J. Gadsby and Kristj{\'a}n Orri Helgason and Elizabeth M Dickson and Jonathan M Mills and Diane S. J. Lindsay and Giles F. S. Edwards and Mary F. Hanson and Kate E. Templeton},
  journal={The Journal of infection},
  year={2016},
  volume={72 2},
  pages={161-70}
}
OBJECTIVES Urinary antigen testing for Legionella pneumophila serogroup 1 is the leading rapid diagnostic test for Legionnaires' Disease (LD); however other Legionella species and serogroups can also cause LD. The aim was to determine the utility of front-line L. pneumophila and Legionella species PCR in a severe respiratory infection algorithm. METHODS L. pneumophila and Legionella species duplex real-time PCR was carried out on 1944 specimens from hospitalised patients over a 4 year period… CONTINUE READING
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