Molecular diagnosis and therapy of kidney cancer.

@article{Linehan2010MolecularDA,
  title={Molecular diagnosis and therapy of kidney cancer.},
  author={W. Marston Linehan and Gennady Bratslavsky and Peter L Choyke and Laura S. Schmidt and Leonard M. Neckers and Donald P Bottaro and Ramaprasad Srinivasan},
  journal={Annual review of medicine},
  year={2010},
  volume={61},
  pages={329-43}
}
Kidney cancer is not a single disease; it is made up of a number of cancers that occur in the kidney, each having a different histology, following a different clinical course, responding differently to therapy, and caused by a different gene. Study of the genes underlying kidney cancer has revealed that it is fundamentally a metabolic disorder. Understanding the genetic basis of cancer of the kidney has significant implications for diagnosis and management of this disease. VHL is the gene for… CONTINUE READING

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