Molecular detection of low-level disease in patients with cancer.

@article{Burchill2000MolecularDO,
  title={Molecular detection of low-level disease in patients with cancer.},
  author={Susan Ann Burchill and Peter John Selby},
  journal={The Journal of pathology},
  year={2000},
  volume={190 1},
  pages={6-14}
}
The accurate detection of low-level disease in patients with cancer is essential to improve the staging of disease and consequently to define appropriate treatment strategies. Most methods currently used for staging are based on imaging studies and histological and immunocytochemical analysis of tissues such as bone marrow aspirates, or antibody assays for marker proteins secreted into the circulation. These methods have limited sensitivity. However, assays for nucleic acid-based markers may be… CONTINUE READING
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