Molecular detection of drug resistant polymorphisms in Plasmodium falciparum isolates from Southwest, Nigeria

  title={Molecular detection of drug resistant polymorphisms in Plasmodium falciparum isolates from Southwest, Nigeria},
  author={M. Tola and O. Ajibola and Emmanuel Taiwo Idowu and O. Omidiji and S. Awolola and A. Amambua-Ngwa},
  journal={BMC Research Notes},
Objective Nigeria bears 25% of global malaria burden despite concerted efforts towards its control and elimination. The emergence of drug resistance to first line drugs, artemisinin combination therapies (ACTs), indicates an urgent need for continuous molecular surveillance of drug resistance especially in high burden countries where drug interventions are heavily relied on. This study describes mutations in Plasmodium falciparum genes associated with drug resistance in malaria; Pfk13, Pfmdr1… Expand

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